Pai R. et al., 2021:Energy-Based Therapies for Erectile Dysfunction: Current and Future Directions.

Pai R, Ory J, Delgado C, Ramasamy R.
Department of Urology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Technologico de Monterrey, School of Medicine and Health Science, Avenue Morones Prieto 3000, Monterrey, Nuevo León 64710, Mexico.
Department of Urology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.

Abstract

Energy-based therapies are novel treatments for erectile dysfunction that are thought to work by stimulation of tissue vasodilation, neoangiogenesis, and so forth. Low-intensity extracorporeal shock wave therapy (Li-ESWT) is the energy-based therapy with the most robust evidence basis demonstrating efficacy and safety. Among this evidence, randomized controlled trials (RCTs) evaluating Li-ESWT have largely been focused on responders to phosphodiesterase-5 inhibitors. Many of these RCTs have limitations including short follow-up durations, inconsistent protocols, and small sample sizes. Until more diverse patient populations are studied and these limitations are addressed, the use of Li-ESWT should remain limited to IRB-approved clinical research trials.
Urol Clin North Am. 2021 Nov;48(4):603-610. doi: 10.1016/j.ucl.2021.06.013. Epub 2021 Aug 12. PMID: 34602179 Review