Northern Germany relies on TPS: Klinikum Wahrendorff and private practice in Hamburg opt for the NEUROLITH


In early May 2021, two more NEUROLITH® systems were installed in Germany. Both the renowned Klinikum Wahrendorff in Sehnde near Hanover and the private practice of Prof. Dr Musa Citak in Hamburg are expanding their range of therapies with Transcranial Pulse Stimulation (TPS®).

The Klinikum Wahrendorff, led by chief physician Prof. Dr Marc Ziegenbein opened in May 2021 a new, modern treatment centre specifically for the early stimulation/maintenance of the mental abilities of people with Alzheimer's disease. Transcranial Pulse Stimulation (TPS®) with the NEUROLITH® is part of the special therapy offer.

In addition, patients with Alzheimer's dementia can now also be treated with the NEUROLITH® system in Hamburg. Prof. Dr Citak was one of the first doctors in northern Germany to opt for the TPS® system. »The first few patients are making very good progress. Relatives are very surprised and pleased by the positive effect,« says Prof. Dr Citak. In his private practice, the shock wave expert also uses various shock wave systems as well as a system for Extracorporeal Magnetotransduction Therapy (EMTT) from STORZ MEDICAL.

TPS Treatment with NEUROLITH system at Clinic Wahrendorff

Left: TPS treatment with the NEUROLITH system / Right: Prof. Dr Marc Ziegenbein and Oliver Rosenthal

About TPS® treatment
In 2018, Transcranial Pulse Stimulation (TPS®) with the NEUROLITH® system was the first, and hitherto only, procedure of its kind to obtain market authorization for the »treatment of the central nervous system of patients with Alzheimer’s disease«. TPS® can stimulate deep cerebral regions, reaching as much as 8 cm into the brain.

Studies conducted at the University of Vienna under the direction of Prof. Dr Roland Beisteiner demonstrated a significant increase in cognitive performance in the CERAD test and a decrease in the Becks Depression Index in patients with mild to moderate dementia.1 In addition, a significant correlation between neuropsychological improvement and cortical thickness increase in AD-critical brain areas was found after TPS® treatment.2

In an ongoing study, Professor Beisteiner is investigating the effect of TPS® therapy on the course of the disease in patients with Parkinson's.

1. Beisteiner R, Matt E, Fan C, Baldysiak H, Schönfeld M, Philippi Novak T, Amini A, Aslan T, Reinecke R, Lehrner J, Weber A, Reime U, Goldenstedt C, Marlinghaus E, Hallett M, Lohse-Busch H. Transcranial Pulse Stimulation with Ultrasound in Alzheimer's Disease-A New Navigated Focal Brain Therapy. Adv Sci (Weinh). 2019 Dec 23;7(3):1902583. doi: 10.1002/advs.201902583. PMID: 32042569; PMCID: PMC7001626.
2. Popescu T, Pernet C, Beisteiner R. Transcranial ultrasound pulse stimulation reduces cortical atrophy in Alzheimer's patients: A follow-up study. Alzheimers Dement (N Y). 2021 Feb 25;7(1):e12121. doi: 10.1002/trc2.12121. PMID: 33681449; PMCID: PMC7906128.



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Wednesday, 22 March 2023