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Clinical Study Results of »Revascularization« with Cardiac Shock Wave Therapy (CSWT)

Shock waves are longitudinal mechanical waves (acoustic waves). They interact with cells of the body by mechanotransduction.

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Shock waves for cardiac use are generated outside the body in a water filled therapy head and coupled to the skin via a flexible membrane. Under simultaneous ultrasound control precise focussing and scanning of predetermined target areas is performed.

After the application of several thousand pulses of low energy shock waves, repair mechanisms are stimulated which result in neogenesis of small vessels. This leads to a reduction of angina and overall improvement of cardiac function and metabolism. Treatment is done without anaesthesia and pain sensation. Five and seven year follow-up data are published.

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Clinical study results »Revascularization«

CSWT

  • is painfreere
  • quires no anaesthesia
  • has 5 and 7 years follow-up
  • has no treatment related side effects
  • efficiency is proven by randomized placebo controlled studies

CSWT increases

  • Perfusion
  • Ejection fraction
  • Performance during exercise training
  • Endurance during 6 minutes walk
  • Oxygen uptake
  • Ischemic treshold syndrome
  • VEGF and receptor
  • Capillary density
  • Wall thickening fraction
  • Regional mean blood flow

CSWT decreases

  • Angina pectoris CCS
  • NYHA functional class
  • NTG use
  • Hospitalization
  • Arrhythmia

General CSWT indications

  • Non-revascularizable Angina pectoris
  • Ischemic heart disease (HF)
  • No-reflow after PCI
  • Diffuse coronary artery disease

Sources:

Schmid JP et al.: Cardiac Shock Wave Therapy for Chronic Refractory Angina Pectoris. A Prospective Placebo-Controlled Randomized Trial

Gabrusenko SA et al.: An experience of the use of a curative method of cardiac shock wave therapy in patients with ischemic heart disease

Khattab A et al.: Extracorporeal cardiac shock wave therapy: First experience in the everyday practice for treatment of chronic refractory angina pectoris

Kikuchi Y et al.: Double-Blind and Placebo-Controlled Study of the Effectiveness and Safety of Extracorporeal Cardiac Shock Wave Therapy for Severe Angina Pectoris

Yang P et al.: Randomized and double-blind controlled clinical trial of extracorporeal cardiac shock wave therapy for coronary heart disease

Wang Y et al.: Cardiac Shock Wave Therapy Reduces Angina and Improves Myocardial Function in Patients With Refractory Coronary Artery Disease

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Friday, 18 August 2017
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